If you wish to translate Eastern European languages into English, go to Google Translate The list of languages includes: Belarusian, Bugarian, Czech, Estonian, Hungarian, Latvian, Lithuanian, Polish, Romanian, Russian, Serbian, Slovak, Slovenian.
JewishGen would be the best place to start. Try the Towns Finder feature...it is a free service and you may be lucky to connect with other descendants.
Jewish Gen - http://www.jewishgen.org/
This is a Virtual Sztetl website that is more useful for Poland and Belarus but you may be able to find some useful info there
The best contact and resource for Eastern Europe is in Belarus. Name is Yuri Dorn...he is very knowledgeable, professional and always willing to help.
DNA Shoah Project - http://www.dnashoah.org/
Stephen P. Morse - http://stevemorse.org/
The Shoah Victims' Names Recovery Project - http://www1.yadvashem.org/yv/en/remembrance/names/index.asp
U.S. Holocaust Museum - http://www.ushmm.org/
Yad Vashem - http://www.yadvashem.org
Yizkor Book Project - http://www.jewishgen.org/yizkor/